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Copyright 2000 Globe Newspaper Company  
The Boston Globe

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January 23, 2000, Sunday ,THIRD EDITION

SECTION: NATIONAL/FOREIGN; Pg. A1

LENGTH: 1619 words

HEADLINE: HOLBROOKE PUTS UN FOCUS ON AFRICA'S WARS, AIDS EPIDEMIC

BYLINE: By Sam Allis, Globe Staff

BODY:
NEW YORK - It's Africa month at the United Nations, produced and directed by Richard Holbrooke.

As impresario, the US ambassador has earned kudos for using his role as temporary president of the Security Council to orchestrate an unprecedented focus on the troubled sub-Saharan region.   From Vice President Al Gore to Nelson Mandela and a half-dozen sub-Saharan leaders, Holbrooke has assembled a strong cast to deliver a pointed message to UN diplomats and the rest of the world that, morality tone poems aside, war and an AIDS pandemic will destroy the continent if left unaddressed. And they threaten the rest of the world as well.

Yet when Holbrooke turns over the seat to his Argentine counterpart at the end of the month, the limits of rhetorical power will be clear. After the wave of Africa oratory has crested, the same intractable issues will remain.

To wit: How can the bloodshed in Burundi, the Congo, and Angola be stopped for good? How can the sexual behavior of men and women in the region be altered to reduce HIV transmission rates? Where is the moral and political backbone of African leaders to stop war and destigmatize HIV? What is the proper posture of the developed world in general, and the United States in particular, in all of this?

And, perhaps thorniest of all, what role will the pharmaceutical giants play in an African AIDS solution?

Holbrooke has lauded Gore for his UN address Jan. 10 on AIDS at the first Security Council meeting in the organization's history to address a health issue. Gore promised at that time to help poor countries obtain anti-HIV medicine at affordable prices, and pledged to increase by $100 million the US commitment to fight AIDS in Africa, bringing the total for its worldwide program to $325 million.

Neither Holbrooke nor Gore has provided specifics about how such inexpensive medical help will materialize. And while the increase in funding is admirable, it remains puny compared to the $1.6 billion that the Clinton administration proposed last week in foreign aid to Colombia to fight the drug war there. In Washington Realpolitik, drugs at home trump AIDS abroad.

The Security Council meeting on AIDS was historic less for the presence of Gore, the first sitting vice president to chair the body, than for the belated recognition that health crises are security concerns.

It shattered the distinction between "soft" and "hard" issues, according to Holbrooke, that has been delineated by Joseph Nye, head of Harvard's John F. Kennedy School of Government and a former Clinton State Department official.

"Many of us have believed since the end of the Cold War that the definition of security had to be broadened to include these issues," Holbrooke said in an interview last week at his office across the street from the United Nations. "Joe Nye should stop making those distinctions, because while they may work as a taxonomy at the Kennedy school, they work to the disadvantage of his goal in the real world."

Semantics aside, the harrowing numbers are now familiar to much of the public: More than 22 million people in sub-Saharan Africa carry HIV, almost 14 million have died from the disease, another 30 million will die in the next 20 years. Each day, 11,000 new HIV infections occur.

As public awareness grows, so will the pressure on pharmaceutical giants like Bristol-Myers Squibb, Merck, and Glaxo Wellcome to provide, at reduced cost or for free, more of their life-saving anti-HIV medicine such as AZT, 3TC, and protease inhibitors.

At the World Trade Organization meeting last month in Seattle, Clinton offered vague words about relaxing the international intellectual property laws that protect the rights of the pharmaceutical companies over the drugs they have invested hundreds of millions of dollars to develop.

"Intellectual property protections are very important to a modern economy," Clinton said. "But when HIV and AIDS epidemics are involved, and like serious health care crises, the United States will henceforward implement its health care and trade policies in a manner that ensures that people in the poorest countries won't have to go without medicine they so desperately need."

No one knows just what this means. But some in the pharmaceutical industry are clear about what it will not tolerate. "We are not willing to abandon our intellectual property rights," said Shannon Herzfeld, vice president for international affairs of the Pharmaceutical Research and Manufacturers of America, the Washington-based industry trade group. "They are our lifeblood."

Most of the large outfits Herzfeld represents have launched their own projects in sub-Saharan Africa to improve the health care delivery systems there. Last year, for example, Bristol-Myers launched a $100 million program called "Secure the Future" to train health care professionals and build health infrastructures in five countries.

According to the World Bank, sub-Saharan countries spent about $5 per person on health care between 1990 and 1995. The annual per-capita income in the region, excluding South Africa, is about $300. Activists concede that these countries would be unable to distribute and monitor anti-AIDS medication today even if the pharmaceuticals decided to give away their medicine to the HIV-infected poor.

Critics have dismissed such efforts as window dressing. "A few million dollars here and a few million there do not constitute a good-faith effort," said Sandy Thurman, who heads the White House AIDS office. "At the end of the day, somebody has to budge."

The industry as a whole has yet to consider a comprehensive, long-term program addressing the incendiary issue of reduced pricing of their anti-AIDS drugs for poor African countries.

At the root of their hesitancy is the specter of activists in this country demanding similar discounts here as well. And if the industry bends on AIDS, what about heart disease? Or hypertension? Where do you draw the line? Also, more than 90 percent of new HIV infections occur in developing countries that are least able to pay for treatment.

Differential pricing scares the pharmaceuticals. "As an industry, we can't address that. The individual companies make those decisions all the time," Herzfeld said, referring to a tiered approach. "I don't think we can get together and carve up the world in terms of pricing."

Holbrooke doesn't buy it. "They have to," he countered. "This is a catastrophic epidemic of plague dimensions. They are all beginning to recognize, belatedly, that the policy has to evolve."

Yet movement has been glacial. Peter Young, who used to direct Glaxo Wellcome's global HIV business and now runs Alphavax, a small North Carolina biotech firm working on an AIDS vaccine, knows the industry well.

"If the industry had been dealing with this whole thing constructively, they could have preempted a lot of this," he said. "It's always an easy choice to stay in the bunker. Most at this point are keeping their heads down and hope it will just move on."

Some activists are about to mount a public campaign vilifying the pharmaceutical groups to force them to bend. The Rev. Eugene Rivers, the Boston minister who has launched a much-publicized program to change sexual practices in sub-Saharan region, is girding for battle.

"The utopian view, which will go nowhere, is that they should surrender their claims on intellectual property. It's a silly proposition," Rivers said. "The more realistic is a knock-down, drag-out public fight that will lead to a negotiated settlement. There has not yet been a full-scale movement to transform them into the moral equivalent of Bull Connors."

Strong stuff. And counterproductive, according to Seth Berkley, president of the International AIDS Vaccine Initiative, a New York-based nonprofit group that works with pharmaceuticals to find a cure. "That's the worst thing we could do," he said of the Rivers stratagem. "They need carrots, not sticks. Our challenge is to get them to the table. You have to protect intellectual property. Otherwise, a company will say, 'We'd rather make Viagra.' "

Funded in part by Bill and Melinda Gates, who have donated $25 million, the International AIDS Vaccine Initiative has a pot of $80 million to provide venture capital to biotech companies working on an AIDS vaccine. Rather than take an equity position, it gains the marketing rights for the drugs, at cost, plus a small percentage in developing countries.

Berkley is convinced that tiered pricing is critical to an AIDS solution in Africa. But the pharmaceuticals need the political cover of governments to adopt that approach. Thus far, such backing has been absent, according to Young.

"Western governments must aggressively say that differential pricing must be part of the picture," he said. "I can't think of a single Western government that has made an official statement that they applaud differential pricing, or that they will structure tax breaks or incentives based on price breaks."

Holbrooke agreed with the tiered approach in principle, but he steered clear of the specifics that flummox all sides. And he flatly rejects the notion that the United States can affect change in the sexual behavior of sub-Saharan Africans. "This is the role of the local leaders," he said. "Even if we want to, the United States cannot go out and do this."

His month of focus on Africa, then, is a campaign of words. The hard part must occur elsewhere. Come February, his rhetorical playbook on the AIDS pandemic gets thin. Then, when the klieg lights are dark, it remains to be seen what his January offensive will have produced. One need not be a cynic to wonder.

GRAPHIC: PHOTO, The US envoy, Richard Holbrooke (right), and Secretary General Kofi Annan, flanking Senator Jesse Helms as he spoke to the UN last week. / REUTERS PHOTO

LOAD-DATE: February 12, 2000




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