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Copyright 2001 The New York Times Company  
The New York Times

August 4, 2001, Saturday, Late Edition - Final

SECTION: Section A; Page 14; Column 1; Editorial Desk 

LENGTH: 655 words

HEADLINE: From Cloning to Cures

BODY:
In a backlash against the onrush of biomedical research into areas that raise moral and ethical issues, the House of Representatives passed a bill this week that would ban all human cloning and subject anyone who violates the ban to criminal penalties and huge civil judgments. Unfortunately, in their zeal to legislate morality and cover their flanks from the religious right, the legislators may put a crimp in research that has promising medical benefits. Once the nature of the work is understood, most citizens would accept the very limited form of cloning involved as a useful scientific tool.

Congress seems to have been spooked by an exaggerated fear that science is going too far too fast. The summer started with President Bush wrestling with an issue that seems, by contrast, relatively simple -- whether to allow federal funding of research on stem cells derived from very early stage embryos, called blastocysts, that are produced in surplus at fertility clinics. This issue raises moral and ethical questions because religious conservatives consider the blastocysts an early form of human life, potentially capable of growing into a fetus and ultimately a newborn child. Others, including this page, consider the blastocysts to be microscopic balls of cells that have no chance of becoming human in a petri dish outside the womb. They are fit subjects for research on therapies that could benefit all humankind.

Many legislators found this research easy to accept because it involves gaining medical benefit from surplus embryos that would be destroyed by the fertility clinics in any event. Then came word that scientists in Virginia had created their own blastocysts from scratch, and that a small biotechnology company in Massachusetts planned to clone them from adult cells. The House dug in its heels quickly, frightened by visions of Dolly the cloned sheep and boasts by fringe groups that somehow, somewhere, they intend to clone a human being.

The legislators were overreacting. The cloning would be used only to create a clump of cells for research to devise cures for devastating diseases. The company had no intention of implanting the blastocysts in a womb in a misguided attempt to produce a cloned child -- an area where Congressional intervention would be appropriate.

The Human Cloning Prohibition Act of 2001 passed the House by a hefty 265-to-162 margin. If the Senate concurs, it would make human cloning a criminal offense carrying penalties of up to 10 years in jail and would impose civil penalties, if pecuniary gain is involved, of at least $1 million, even if the cloning was for therapeutic purposes. That would be a shame, given the nature of the work proposed.

The Massachusetts company simply wants to remove the nucleus from a female donor's egg, insert a cell from the skin of another donor, and then stimulate the egg to reprogram the genes of the skin cell to start growing into a blastocyst. The company would then derive stem cells from the blastocyst and try to coax them into becoming virtually any kind of cell needed to repair the human body, potentially providing treatments for a wide range of ailments, from Alzheimer's to heart disease.

The cloning approach has one tremendous advantage over using stem cells from surplus embryos at fertility clinics -- the resulting therapeutic cells would be genetically matched to the patient who provided the skin cell, making any treatment far more likely to work. This is an area of research that should not be foreclosed simply because some people regard the blastocyst as sacrosanct or because they fear a slippery slope toward reproductive cloning of humans. President Bush opposes all human cloning. But the Senate needs to take a more discriminating approach that would allow therapeutic cloning and simply ban reproductive cloning, which is too dangerous to attempt now and which most legislators find abhorrent.  

http://www.nytimes.com

LOAD-DATE: August 4, 2001




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