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ASRM BULLETIN
Volume 3, Number 16
July 20, 2001

This Week in the Stem Cell and Cloning Debates

Stem Cells

It has been another busy week in the stem cell debates in the nation’s capitol. On Tuesday, there was a hearing in the House on stem cell research. Much of the testimony was negative. Among the witnesses were the parents of a set of twins who had been born following an embryo donation. Led by ardent right-to-life Congressman Chris Smith (R- NJ) the twins were used to show that frozen embryos could become children and therefore using embryos for research purposes was taking a life.

Prior to the hearing, there were dueling press conferences. The pro-stem cell side featured several prominent members of Congress and children suffering from diseases that could be helped by stem cell research.

On Wednesday, the action moved over to the Senate side for a stem cell hearing. The big news on Wednesday was the release of a long-awaited NIH report on the possibilities of future benefits from embryonic stem cell research. The report makes it clear that there is great potential in embryonic stem cells. (the report is available at http://www.nih.gov/news/stemcell/index.htm)

The other big news on Wednesday was the announcement from Senator Bill Frist (R-TN) that he supported federal funding for embryonic stem cell research. Senator Frist was a heart surgeon prior to his political career, and is very close to President Bush. Frist released a 10 point plan, which included no federal funding for derivation of embryonic stem cell lines, a limit to the number of lines created and making illegal all forms of cloning and the creation of embryos for research purposes. ASRM obviously welcomes Senator Frist’s support for stem cell research, but has some concerns about his proposed conditions.

These two events overshadowed the appearance of two ASRM members at the hearing. William Gibbons, MD and Susan Lanzendorf, PhD from the Jones Institute at EVMS were invited to testify about their work using donor gametes to begin embryonic stem cell lines. They provided informative statements at the hearing, but most of the attention centered on the NIH report and Senator Frist’s announcement.

The media coverage was extensive this week. Several web portals have now dedicated sections of their web sites to the stem cell issue. Including:

Yahoo/Reuters http://dailynews.yahoo.com/fc/Science/Stem_Cell_Research/

Time Magazine http://www.time.com/time/2001/stemcells/

PBS/NewHour http://www.pbs.org/newshour/health/stemcells.htm


Cloning


The House is continuing its work on cloning legislation. Yesterday, the Crime subcommittee of the House Judiciary Committee approved a new version of the Weldon bill. Now numbered HR 2505, this overly broad bill would prohibit any use of cloning technology in humans, even those not for reproductive purposes.

It is expected that both the Weldon bill and the Greenwood bill will be dealt with in committee next week. There has been talk of floor action before Congress leaves for August recess, but that is unlikely. ASRM has supported the Greenwood bill (currently HR 2172, but a new version is expected out next week) which would make human reproductive cloning illegal, but allow research or therapeutic uses of somatic cell nuclear transfer.

The National Academy of Sciences is working on a cloning report and is having an information gathering meeting on August 7 in Washington DC. They have asked us forward their invitation to subscribers to the ASRM Bulletin. The letter follows:

Scientific and Medical Aspects of Human Cloning

The questions surrounding human cloning are controversial and growing more complicated, especially as animal-cloning efforts move forward. The nation needs a clear, unbiased examination of the state of the science in this area as lawmakers and the public grapple with public policy and ethical issues. A joint panel of the National Academies' Committee on Science,
Engineering, and Public Policy and the Board on Life Sciences has undertaken a study to review the relevant scientific and medical research on human cloning as well as closely related issues regarding scientific and medical ethics. As part of its work, the committee will conduct an
information-gathering meeting on August 7.

Because of confusion outside the scientific community concerning the differences between human cloning and embryonic stem-cell research, the study also will explain the distinctions between these two endeavors. It will assess the current status of animal cloning, including outcomes of
previous trials; whether knowledge of assisted reproductive technologies can be applied to cloning a human; criteria that should be used to evaluate the safety of human cloning; and public policy issues, including responsible conduct of research. The panel will recommend a process for
evaluating future research and address whether there should be a moratorium on human cloning.

At its workshop on August 7, 2001, the panel will gather information from experts in the field on the following issues:

  1. The scientific issues underlying animal models of cloned versus normal embryonic and fetal development;

  2. The actual outcomes of animal cloning with consideration of possible complications;

  3. The considerable experience of human assisted reproductive technologies (such as in vitro fertilization);

  4. The criteria that should be used to evaluate the safety of reproductive cloning for mother and the cloned offspring;

  5. Responsible conduct of research as well as the protection of human participants (mother, child) in human cloning attempts;

  6. Human cloning and public policy.


All are welcome to attend this event either in person or via Webcast. More information on the study and the workshop including an agenda is available at http://national-academies.org/humancloning.

Because the purpose of the workshop is for the panel to gather information to help it respond to its charge, the panel needs to hear from as many speakers as possible and discuss key issues with those speakers. Since the time period to do this is very limited, questions will only be asked by the panel members and other speakers. Members of the public and press who attend the workshop either in person or via the audio Webcast will not be provided the opportunity to ask questions at the workshop; however, all are welcome to submit comments to the panel, including suggestions for panel questions for the speakers, no later than August 1.

Date: Tuesday, August 7, 2001

Time: 8:30 a.m.

Location: National Academy of Sciences Building, 2101 Constitution Avenue, NW, Washington, DC. Direct taxis to 2100 C Street, NW.

Room: Auditorium

Registration: There is no cost for registration. However, you must register by August 1st for both the workshop and the Webcast. You may do so by visiting the study’s Web site at 
http://national-academies.org/humancloning. More details on how to participate in the Webcast are also located at this site.


THE ASRM Bulletin is a publication of the American Society for Reproductive Medicine’s Office of Public Affairs. It is intended as an information resource for our members, and should not be quoted or cited without the expressed permission of ASRM. For questions or comments call 202-863-4985 or email asrm-dc@asrm.org

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