Embargoed: June
2, 2002, 2:00 p.m. est.
Contact:
Julie Kimbrough, 646-734-6091
Maggie Goldberg,
973-379-2690, ext.115
PATIENT GROUPS RESPOND TO STUDY SHOWING NUCLEAR
TRANSPLANTATION CAN ELIMINATE TISSUE REJECTION IN ANIMALS
Coalition for the Advancement of Medical Research
Against Using This In Humans
Washington, DC -- June 3, 2002
-- The Coalition for the Advancement of Medical Research (CAMR)
reacted today to the Advanced Cell Technology (ACT) study showing
that nuclear transplantation (therapeutic cloning) can be used to
generate immune-compatible tissues. The research, reported in the
July issue of Nature Biotechnology, uses renal cells from a cloned
bovine fetus to generate functional immune-compatible renal tissues.
"While the research ACT conducted in this study demonstrates some
important proof of principles for nuclear transplantation (or
therapeutic cloning), clearly the research methods used in this
experiment should not be applied in humans," said Michael
Manganiello, President of CAMR, the patient and research advocacy
group which led the advocacy efforts to allow federal funding of
embryonic stem cell research. "CAMR is opposed to reproductive
cloning or any use of the technology that allows a transfer into a
woman's uterus. We support legislation, such as Senate Bill S. 2439
promoted by Senators Specter, Feinstein, Hatch and Kennedy, which
would make that illegal."
"The ACT announcement comes at a critical time during the Senate
debate on therapeutic cloning. While the research in animal models
shows that it may be possible to use cloning to generate tissues and
eliminate tissue rejection, it's important for the American public
to understand that the methods used in this animal experiment should
not be pursued in humans," said Christopher Reeve, Chairman of the
Christopher Reeve Paralysis Foundation. "Research involving the
implantation of a human embryo into a woman, even to derive
life-saving cells, crosses a very important line and we need to pass
legislation that would prohibit it. Although I am a patient living
with a severe spinal cord injury, I can say without any reservation
whatsoever, that I do not support the implantation of embryos into
humans to derive medical treatments."
Therapeutic cloning is fundamentally different from human
reproductive cloning; therapeutic produces stem cells, not babies.
In therapeutic cloning, the nucleus of a donor's unfertilized egg is
removed and replaced with the nucleus of a patient's own cells, like
a skin, heart, or nerve cell. These types of cells are called
somatic cells. NO sperm is used in this procedure. The cells are not
transplanted into a womb. The unfertilized egg cells are stored in a
petri dish to become a source of stem cells that can be used to
treat currently incurable medical conditions. SCNT aims to treat or
cure patients by creating tailor-made, genetically identical cells
that their bodies won't reject. In other words, SCNT could allow
patients to be cured using their own DNA.
A poll commissioned by the Coalition for the Advancement of
Medical Research (CAMR) shows that more than two thirds of Americans
support therapeutic cloning research to produce stem cells for
treating life-threatening diseases and want the government to allow
it to proceed. Less than 30% want to outlaw the research. In the
poll, conducted from April 18 to April 21, 68% of those surveyed
said they favored the government allowing scientists to conduct
therapeutic cloning research, while only 26% opposed it.
The Coalition for the Advancement of Medical Research (CAMR),
is comprised of nationally-recognized patient organizations,
universities, scientific societies, foundations, and individuals
with life-threatening illnesses and disorders, advocating for the
advancement of breakthrough research and technologies in
regenerative medicine - including stem cell research and somatic
cell nuclear transfer - in order to cure disease and alleviate
suffering. For more information on CAMR, visit the website:
www.camradvocacy.org