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Somatic Cell Nuclear Transfer (SCNT) Definitions

Adult Stem Cell: Cell taken from mature tissue that can renew itself but has limited ability to transform into specialized cell types.

Cloning: Creating a genetically identical organism. While much attention has been paid to reproductive cloning, other types of cloning have been in use for years and have led to several breakthroughs in agricultural production, DNA forensic evidence, and biotechnology.

Blastocyst: A clump of 30 to 150 cells that has not been implanted into a uterus.

Differentiation: The process by which early, unspecified cells acquire features of specific cells, such as heart, liver, or muscle tissue.

Embryonic Stem Cell: Cell taken from an embryo that has the potential to become a wide variety of specialized cells.

Nucleus: The core of a cell that contains chromosomes.

Regenerative Medicine: Repairing the body through its own regenerative mechanisms-including stem cells-to renew damaged tissues and organs.

Reproductive Cloning: The practice of attempting to create a human being who is an exact genetic copy of a particular individual. The key difference between SCNT and reproductive cloning is that stem cells for SCNT are kept in petri dishes for disease research, while stem cells for reproductive use are transferred to a uterus in anticipation of birth.

Somatic Cell Nuclear Transfer (SCNT): The practice of using a patient's own cells to repair his or her body. This involves removing the nucleus of an unfertilized donor egg cell, replacing it with the nucleus of a somatic (living) cell from the patient's body, and stimulating that cell to divide to provide stem cells for disease research.

Stem Cells: Master cells that can divide and reproduce indefinitely to form specialized cells of tissues and organs.

Therapeutic Cloning: Another term for SCNT.





Coalition for the Advancement of Medical Research
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