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Welcome to

GENETIC CROSSROADS #17

May 16, 2001

Supporting responsible uses of human genetic technologies
Opposing the new techno-eugenics


CONTENTS

I. EDITORS' NOTE

II. HUMAN CLONING UPDATE
1. Report on Cloning Legislation in US Congress
2. UK Health Secretary Recommends Cloning Ban
3. Prominent Scientists Support Cloning Ban in Science
4. Debate on Embryo Cloning in Nature Medicine

III. OTHER NEWS AND POINTERS
1. Gerhard Shroder Rejects Human Genetic Manipulation
2. James Watson on the "Next Step for Science"

IV. EVENTS AND RESOURCES
1. Beyond Biodevastation 2001, San Diego, June 22-23
2. Extropy Institute Conference, San Jose, June 15-17
3. Redesigning Life: The Worldwide Challenge to Genetic
Engineering

4. Made not Born: The Troubling World of Biotechnology

V. ABOUT GENETIC CROSSROADS


I. EDITORS' NOTE

Since the beginning of the year human cloning has become a live political
issue in countries around the world. Even in the United States, where the
technologies of human genetic manipulation are being most aggressively
promoted, a federal cloning ban will soon be debated. (See below.)

A US ban on human cloning would be an important step toward bringing
human genetic and reproductive technologies under societal control. But
it would be only a first step. The US must also join those countries
that have already outlawed human germline engineering. This technology,
which would allow the production of genetically "enhanced" children,
would serve as the keystone of a frankly eugenic agenda that has
gathered a disturbing number of adherents among scientists and others.

"Genetic enhancement" has also been in the news of late: on the front
page of the New York Times (May 11, "Someday Soon, Athletic Edge May
Be From Altered Genes") and in the May 14 issue of Sports Illustrated
("Unnatural Selection: Genetic Engineering is About to Produce a New
Breed of Athlete Who Will Obliterate the Limits of Human Performance").

Both articles focus on the introduction of genes into existing people.
(Medical experiments with such gene transfer procedures, technically
known as "somatic" genetic engineering, are currently underway in
clinical trials.)

Both articles acknowledge that the use of genetic engineering to
"enhance" individuals would be medically dangerous, and politically
and ethically controversial. But both also contain many claims that
such procedures are inevitable. The NY Times article, for example,
states that "athletes, scientists and sports administrators universally
agree that someone will attempt genetic engineering, if they have not
already." And both blur somatic gene transfer, germline engineering,
and other eugenic practices such as the purchase of human eggs from
women thought to be in some way "superior."

As techno-eugenic advocate Gregory Stock writes, "[H]uman cloning is
most significant as a symbol: it has served notice that humanity is
going to change more than the landscape we inhabit. . .Whether or not
human cloning is banned will have little impact on that critical
transformation because biotechnology is racing ahead on a broad front."
Gregory Stock, The Prospects for Human Germline Engineering, 1/29/99,
<www.heise.de/tp/english/inhalt/co/2621/1.htm>.


II. HUMAN CLONING UPDATE

1. Report on Cloning Legislation in Congress

As of May 14, seven bills have been introduced in the US Congress to
ban human cloning. The major difference among them turns on whether
a ban should apply only to the creation of cloned people (reproductive
cloning) or also to the creation of cloned human embryos for purposes
of medical experimentation (embryo cloning.)

Supporters of embryo cloning say it may have important therapeutic
applications. Opponents say its therapeutic applications do not appear
promising, and that it opens a very wide door to reproductive cloning
and to germline engineering.

In the past, most opponents of embryo cloning have been conservatives
and anti-abortion forces; most of those willing to support it have been
liberals. Now, however, progressives, liberals, and environmental and
women's health leaders are beginning to speak more supportively of a
complete ban on all varieties of human cloning. Left-liberal Dennis
Kucinich (D-OH), for example, chair of the House Progressive Caucus,
has signed on as a co-sponsor of the bill banning both embryo cloning
and reproductive cloning (the "Weldon Bill," HR1644).

Hearings may be held by the House Judiciary Committee and the Energy
and Commerce committee in mid-June, and the full House could vote on a
cloning ban as early as mid-July or August. If a bill passes the House,
action will begin on the Senate side in earnest, perhaps in late summer
but more likely early fall.

The biotech industry is stronger in the Senate than in the House. The
shape of anti-cloning legislation may depend on whether key liberals,
mostly Democrats but including some Republicans, will vote for a more
comprehensive ban even though it is favored by conservative legislators,
or for the narrower approach favored by the biotech industry.


2. UK Health Secretary Recommends Cloning Ban

The British Secretary of State for Health, Alan Milburn, announced in
mid-April that the government plans to introduce legislation to outlaw
reproductive human cloning. UK media coverage noted that the proposed
ban is meant "to ease public fears about genetic technology."

Reproductive cloning in the UK is currently under the control of the
Human Fertilisation and Embryology Authority, which has stated that it
will not approve it. Milburn said the government believes that producing
humans by cloning "should be banned by law, not just by licence."

Milburn also announced funding proposals and other plans to ensure that
Britain "remains on the cutting edge of genetic technology."
<http://news.independent.co.uk/uk/science/story.jsp?story=67472>


3. Prominent Scientists Support Cloning Ban in Science

The March 30 issue of Science magazine includes a letter titled "Don't
Clone Humans!" from Rudolph Jaenisch of the Whitehead Institute and Ian
Wilmut, head of the team at the Roslin Institute that produced "Dolly,"
the first mammal to be cloned from an adult.

"There are many social and ethical reasons why we would never be in
favor of copying a person," Jaenisch and Wilmut wrote. "However, our
immediate concern is that this proposal fails to take into account
problems encountered in animal cloning."

The authors distinguish between "copying a person" (reproductive
cloning) and "therapeutic cell cloning," which they support.
<http://www.sciencemag.org/cgi/content/full/291/5513/2552> (fee)


4. Debate on Embryo Cloning in Nature Medicine

Though the British government has moved to ban reproductive cloning,
it has recently approved the creation of human embryos by cloning, and
their use to derive embryonic stem (ES) cells. This approval has been
controversial in the UK among both scientists and the public.

In the April issue of Nature Medicine, fertility pioneer Robert Winston
defends embryo cloning and the medical potential of ES cells. Michael
Antoniou, a molecular geneticist at Guy's Hospital in London, argues
that adult stem cells hold more medical promise than do ES cells (while
pointing out that any medical benefits from either variety of stem cells
are years in the future), and that embryo cloning would make both
reproductive cloning and germline engineering far more likely.
<http://www.nature.com/nm/>


III. OTHER NEWS

1. Gerhard Shroder Rejects Human Genetic Manipulation

In an article on German reactions to the legalization of euthanasia in
the Netherlands, the New York Times comments that "so-called bio-politics
are currently under intense review" in Germany. In that context, it
quotes a recent statement by Chancellor Gerhard Schroder: "We agree on
what we do not want: the cloned, optimized, genetically selected human
being." ("Horror Expressed in Germany Over Dutch Euthanasia," New York
Times, April 12).


2. James Watson on the "Next Step for Science"

James Watson has reiterated his support for human germline engineering in
an article in the UK Independent titled "Fixing the human embryo is the
next step for science." "I strongly favour controlling our children's
genetic destinies," Watson writes. A lead story in the newspaper agreed
(April 16). <http://www.independent.co.uk/story.jsp?story=66804>
<http://argument.independent.co.uk/leading_articles/story.jsp?story=66828>

Commenting on these articles, the British weekly on-line publication
BioNews, which is sponsored by AstraZeneca, editorialized that the
"worst outcome would not be a future of genetic underclasses or designer
babies, but one where genetic science has failed to develop because of
our fear of how it might be abused." (BioNews #103, April 17,
<http://www.progress.org.uk/News/BioNewsSearch.html>.)


IV. EVENTS AND RESOURCES

1. Beyond Biodevastation 2001, San Diego, June 22-27

"The Fifth Grassroots Gathering to Celebrate Biodiversity and Question
Genetic Engineering" will feature speakers, panels, and workshops on
the genetic engineering of plants, animals, and humans; as well as
protests targeting the June 24-27 convention of BIO, the Biotechnology
Industry Organization.

Registration is underway and is requested by June 7 (June 1 for help
with arranging housing or child care). Information about schedule,
speakers, and registration is available at <http://www.biodev.org/>.


2. Extropy Institute Conference, San Jose, June 15-17

Proponents of a post-human and techno-eugenic future will gather at
"Extro-5 Conference: Shaping Things to Come." According to a press
release written by Extropy Institute head Max More, "Strident voices
and legislation threaten to hold back progress in biotech, information
technology, the spread of open markets, and the development of
technologies that could cure age-old ailments, extend our lives and
augment our capabilities." <http://www.extropy.org/ex5/extro5.htm>


3. Redesigning Life: The Worldwide Challenge to Genetic Engineering

The anthology Redesigning Life (Brian Tokar, ed. Zed Books: 2001) is
now available in the US and the UK. A Canadian edition from McGill-
Queens University Press and an Australian edition from Scribe
Publications will be available shortly.

The book is divided into four sections: Our Health, Our Food and the
Environment; Medical Genetics, Science and Human Rights; Patents,
Corporate Power, and the Theft of Knowledge; The Worldwide Resistance
to Genetic Engineering.

Contributors include Vandana Shiva, Martha Crouch, Hope Shand, Beth
Burrows, Jack Kloppenburg, Ricarda Steinbrecher, Victoria Tauli-Corpuz,
Marcy Darnovsky, David King, Michael Dorsey, Sarah Sexton, Chaia Heller,
Barbara Katz Rothman, Alix Fano, Zoe C. Meleo-Erwin, Mitchel Cohen,
Kimberly Wilson, Steve Emmott, Thomas Schweiger, and others.
<http://www.zedbooks.demon.co.uk/autumn2000long.htm>


4. Made Not Born: The Troubling World of Biotechnology

The anthology Made Not Born (Casey Walker, ed. Sierra Club Books: 2000)
is now in its second printing.

Contributors include Wendell Berry, Chris Desser, Stuart Newman, David
Loy, Marti Crouch, Andrew Kimbrell, Jack Turner, Richard Hayes,
Catherine Keller, Richard Strohman, Freeman House, Kristin Dawkins,
Martin Teitel, and David Petersen. <http://www.wildduckreview.com/>


V. ABOUT GENETIC CROSSROADS (formerly Techno-Eugenics Email Newsletter)

This newsletter originated in 1999 out of the concerns of academics,
activists, and others in the San Francisco Bay Area about the direction
of the new human genetic and reproductive technologies. It is published
by the Exploratory Initiative on the New Human Genetic Technologies, a
public interest organization working to alert the public and leaders of
civil society about the urgent need for societal oversight of these
technologies and the dangers of the techno-eugenic vision.

We support genetic and reproductive technologies that serve the public
interest. We oppose those--especially human germline engineering and
human reproductive cloning--that would be likely to exacerbate inequality,
the commercialization of reproduction, and the commodification of human
genes and tissues.

GENETIC CROSSROADS is published approximately once a month. Feedback,
submissions, and suggestions are welcome. Marcy Darnovsky will moderate.
Please forward GENETIC CROSSROADS to others who may be interested.

Exploratory Initiative staff, San Francisco:
Marcy Darnovsky, Ph.D. <genetic-crossroads@genetics-and-society.org>
Richard Hayes, M.A. <richard.hayes@genetics-and-society.org>
Tania Simoncelli, M.S. <tania@publicmediacenter.org>
Jesse Reynolds, M.S. <reynolds@nature.berkeley.edu>

Exploratory Initiative staff, Washington DC:
Douglas Hunt, Ph.D. <dhunt@hgtinitiative.org>


More Information

Analysis: Examine the social, cultural, and economic landscape

Perspectives: Explore various communities' concerns regarding human genetic technologies

Policies: Read about existing and potential regulations

Technologies: Learn the basic science and consider arguments for and against